Chlorpheniramine; Hydrocodone

Drug Usage Statistics, United States, 2013 - 2021

Chlorpheniramine; Hydrocodone Summary for 2021

Top drug rank #363 ( 104)
Estimated number of prescriptions in the United States (2021) 52,827
Estimated number of patients in the United States (2021) 32,657
Average total drug cost (USD)  
Per prescription $46.53
Per day of therapy $5.26/day
Average out-of-pocket cost (USD)  
Per prescription $31.32
Per day of therapy $4.27/day

Total Prescriptions and Patients Per Year (2013 - 2021)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2013 383 -
2014 385  2
2015 423  38
2016 407  16
Year Rank Change
2017 377  30
2018 445  68
2019 431  14
2020 467  36
2021 363  104

Drug Cost Over Time (2013 - 2021)

  • Cost Per Prescription Fill: Average cost per filled prescription regardless of how many days of therapy the prescription is filled for (e.g. 10 days, 30 days, 90 days, etc.)
  • Cost per Day of Therapy: The average cost per prescription fill divided by the days of therapy. For example, a 10-day antibiotic course costing $30 would be $3 per day. Similarly, a 30-day supply of an oral antihypetensive costing $30 would be $1 per day.

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2021)

No data available

Distribution of Days Supplied (2021)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Hydrocodone Bitartrate And Chlorpheniramine Maleate
  • Vituz
  • Hydrocodone Polistirex And Chlorpheniramine Polistirex
  • Hydrocodone Polistirex And Chlorpheniramne Polistirex
  • Tussicaps
  • Tussionex Pennkinetic
  • Hydrocodone Bitartrate, Chlorpheniramine Maleate And Pseudoephedrine Hydrochloride
  • Hydrocodone Bitartrate,Chlorpheniramine Maleate And Pseudoephedrine Hydrochloride
  • Zutripro
Generic Drug Synonyms and Salts
  • Chlorpheniramine Maleate; Hydrocodone Bitartrate
  • Chlorpheniramine Polistirex; Hydrocodone Polistirex
  • Hydrocodone Bitartrate; Chlorpheniramine Maleate
  • Hydrocodone; Chlorpheniramine
  • Chlorpheniramine; Hydrocodone

FDA Approval Information

Established Pharmacologic Class (EPC): Histamine-1 Receptor Antagonist, Opioid Agonist
Initial FDA approval date: 12/31/1987
First FDA applicant: Discn
First dosage form: Suspension, Extended Release (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2021. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.01. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Updated Sep 12, 2021
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