Bisoprolol Fumarate; Hydrochlorothiazide

Drug Usage Statistics, United States, 2008 - 2018

Bisoprolol Fumarate; Hydrochlorothiazide Summary for 2018

Estimated number of prescriptions in the United States 1,556,622
Top drug rank #278 ( 48)
Average total drug cost $12.33 (USD)
Average out-of-pocket cost $7.6 (USD)

Number of Prescriptions Over Time (2008 - 2018)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2008 129  41
2009 147  18
2010 184  37
2011 79  105
2012 110  31
2013 247  137
Year Rank Change
2014 211  36
2015 244  33
2016 312  68
2017 326  14
2018 278  48

Drug Cost Over Time (2008 - 2018)

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Related Drugs

Drug Name Total Prescriptions (2018)
Metoprolol 71,581,961
Hydrochlorothiazide 40,575,076
Carvedilol 22,737,639
Atenolol 18,644,885
Hydrochlorothiazide; Lisinopril 15,932,877
Propranolol Hydrochloride 14,571,768
Hydrochlorothiazide; Losartan Potassium 13,880,262
Hydrochlorothiazide; Triamterene 6,007,405
Timolol 4,312,018
Hydrochlorothiazide; Valsartan 3,261,560
Nebivolol Hydrochloride 2,955,158
Labetalol 2,297,672
Dorzolamide Hydrochloride; Timolol Maleate 1,950,346
Bisoprolol Fumarate; Hydrochlorothiazide (this drug) 1,556,623
Bisoprolol Fumarate 1,396,798
Benazepril Hydrochloride; Hydrochlorothiazide 1,001,353

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Bisoprolol Fumarate And Hydrochlorothiazide
  • Ziac
Generic Drug Synonyms and Salts
  • Hydrochlorothiazide; Bisoprolol Fumarate
  • Bisoprolol Fumarate; Hydrochlorothiazide

FDA Approval Information

Established Pharmacologic Class (EPC): beta-Adrenergic Blocker, Thiazide Diuretic
Initial FDA approval date: 3/26/1993
First FDA applicant: Rx
First dosage form: Tablet (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2008-2018. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 21.1. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Updated Jan 18, 2021
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