Bisoprolol Fumarate; Hydrochlorothiazide

Drug Usage Statistics, United States, 2007 - 2017

Number of Prescriptions Over Time (2007 - 2017)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2007 88  2
2008 129  41
2009 147  18
2010 184  37
2011 79  105
2012 110  31
Year Rank Change
2013 247  137
2014 211  36
2015 244  33
2016 313  69
2017 327  14

Patient Out-Of-Pocket Cost Over Time (2007 - 2017)

"Out-of-pocket" cost refers to the payment made by the patient (either cash price or the copay amount). This value does not include reimbursement from a third party payer (eg, Medicare or private insurance) and does not represent the total drug cost.

Usage Statistics of Related Drugs

Drug Name Total Prescriptions (2017)
Metoprolol 68,076,157
Hydrochlorothiazide 42,037,081
Carvedilol 22,974,069
Atenolol 20,208,476
Propranolol Hydrochloride 17,749,819
Hydrochlorothiazide; Lisinopril 16,687,919
Hydrochlorothiazide; Losartan Potassium 11,752,545
Hydrochlorothiazide; Triamterene 7,631,431
Hydrochlorothiazide; Valsartan 5,341,254
Nebivolol Hydrochloride 4,473,865
Timolol 4,369,477
Labetalol 2,420,203
Dorzolamide Hydrochloride; Timolol Maleate 2,135,489
Bisoprolol Fumarate 1,558,830
Atenolol; Chlorthalidone 1,256,080
Bisoprolol Fumarate; Hydrochlorothiazide (this drug) 967,296
Benazepril Hydrochloride; Hydrochlorothiazide 844,857

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Bisoprolol Fumarate And Hydrochlorothiazide
  • Ziac
Generic Drug Synonyms and Salts
  • Hydrochlorothiazide; Bisoprolol Fumarate
  • Bisoprolol Fumarate; Hydrochlorothiazide

FDA Approval Information

Established Pharmacologic Class (EPC): beta-Adrenergic Blocker, Thiazide Diuretic
Initial FDA approval date: 3/26/1993
First FDA applicant: Rx
First dosage form: Tablet (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2007-2017. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 20.1. Read more about the ClinCalc DrugStats database.


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Updated Jul 19, 2018
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