Atropine Sulfate; Diphenoxylate Hydrochloride

Drug Usage Statistics, United States, 2006 - 2016

Number of Prescriptions Over Time (2006 - 2016)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2006 236  61
2007 229  7
2008 204  25
2009 252  48
2010 298  46
2011 365  67
Year Rank Change
2012 280  85
2013 267  13
2014 314  47
2015 320  6
2016 298  22

Patient Out-Of-Pocket Cost Over Time (2006 - 2016)

"Out-of-pocket" cost refers to the payment made by the patient (either cash price or the copay amount). This value does not include reimbursement from a third party payer (eg, Medicare or private insurance) and does not represent the total drug cost.

Usage Statistics of Related Drugs

Drug Name Total Prescriptions (2016)
Tiotropium 8,306,843
Albuterol Sulfate; Ipratropium Bromide 3,774,881
Solifenacin Succinate 3,630,387
Dicyclomine Hydrochloride 3,502,152
Ipratropium 3,400,104
Benztropine Mesylate 2,568,272
Atropine Sulfate; Diphenoxylate Hydrochloride (this drug) 1,247,814
Tolterodine Tartrate 1,214,561

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Colonaid
  • DI-atro
  • Diphenoxylate Hydrochloride And Atropine Sulfate
  • Diphenoxylate Hydrochloride W/ Atropine Sulfate
  • LO-trol
  • Logen
  • Lomanate
  • Lomotil
  • Lonox
  • Low-quel
Generic Drug Synonyms and Salts
  • Diphenoxylate Hydrochloride; Atropine Sulfate
  • Atropine Sulfate; Diphenoxylate Hydrochloride

FDA Approval Information

Established Pharmacologic Class (EPC): Anticholinergic, Cholinergic Muscarinic Antagonist, Antidiarrheal
Initial FDA approval date: Prior to January 1, 1982
First FDA applicant: Discn
First dosage form: Solution (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2006-2016. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 19.1. Read more about the ClinCalc DrugStats database.


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Updated Jul 19, 2018
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