Atropine Sulfate; Diphenoxylate Hydrochloride

Drug Usage Statistics, United States, 2008 - 2018

Atropine Sulfate; Diphenoxylate Hydrochloride Summary for 2018

Estimated number of prescriptions in the United States 765,429
Top drug rank #355 ( 3)
Average total drug cost $42.32 (USD)
Average out-of-pocket cost $10.7 (USD)

Number of Prescriptions Over Time (2008 - 2018)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2008 204  25
2009 253  49
2010 298  45
2011 364  66
2012 281  83
2013 267  14
Year Rank Change
2014 314  47
2015 320  6
2016 297  23
2017 352  55
2018 355  3

Drug Cost Over Time (2008 - 2018)

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Related Drugs

Drug Name Total Prescriptions (2018)
Oxybutynin 7,339,186
Tiotropium 6,762,986
Albuterol Sulfate; Ipratropium Bromide 4,789,979
Dicyclomine Hydrochloride 3,076,089
Ipratropium 2,023,254
Umeclidinium Bromide; Vilanterol Trifenatate 1,821,792
Umeclidinium Bromide 1,814,590
Solifenacin Succinate 1,736,711
Benztropine Mesylate 1,717,960
Tolterodine Tartrate 1,600,521
Atropine Sulfate; Diphenoxylate Hydrochloride (this drug) 765,429

Multum Therapeutic Classes

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Colonaid
  • DI-atro
  • Diphenoxylate Hydrochloride And Atropine Sulfate
  • Diphenoxylate Hydrochloride W/ Atropine Sulfate
  • LO-trol
  • Logen
  • Lomanate
  • Lomotil
  • Lonox
  • Low-quel
Generic Drug Synonyms and Salts
  • Diphenoxylate Hydrochloride; Atropine Sulfate
  • Atropine Sulfate; Diphenoxylate Hydrochloride

FDA Approval Information

Established Pharmacologic Class (EPC): Anticholinergic, Cholinergic Muscarinic Antagonist, Antidiarrheal
Initial FDA approval date: Prior to January 1, 1982
First FDA applicant: Discn
First dosage form: Tablet (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2008-2018. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 21.1. Read more about the ClinCalc DrugStats database.


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Updated Dec 6, 2020
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