Drug Usage Statistics, United States, 2006 - 2016

Number of Prescriptions Over Time (2006 - 2016)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2006 311  40
2007 366  55
2008 410  44
2009 362  48
2010 414  52
2011 433  19
Year Rank Change
2012 394  39
2013 378  16
2014 397  19
2015 488  91
2016 382  106

Patient Out-Of-Pocket Cost Over Time (2006 - 2016)

"Out-of-pocket" cost refers to the payment made by the patient (either cash price or the copay amount). This value does not include reimbursement from a third party payer (eg, Medicare or private insurance) and does not represent the total drug cost.

Usage Statistics of Related Drugs

Drug Name Total Prescriptions (2016)
Tretinoin 1,249,141
Isotretinoin 1,118,664
Adapalene (this drug) 427,499
Adapalene; Benzoyl Peroxide 352,797

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Differin
Generic Drug Synonyms and Salts
  • Adapalene

FDA Approval Information

Established Pharmacologic Class (EPC): Retinoid
Initial FDA approval date: 5/31/1996
First FDA applicant: Discn
First dosage form: Solution (topical)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2006-2016. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 19.1. Read more about the ClinCalc DrugStats database.


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Updated Jul 19, 2018
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