Acetaminophen; Tramadol Hydrochloride

Drug Usage Statistics, United States, 2007 - 2017

Number of Prescriptions Over Time (2007 - 2017)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2007 287  32
2008 301  14
2009 268  33
2010 305  37
2011 317  12
Year Rank Change
2012 338  21
2013 292  46
2014 278  14
2015 276  2
2016 314  38

Patient Out-Of-Pocket Cost Over Time (2007 - 2017)

"Out-of-pocket" cost refers to the payment made by the patient (either cash price or the copay amount). This value does not include reimbursement from a third party payer (eg, Medicare or private insurance) and does not represent the total drug cost.

Usage Statistics of Related Drugs

Drug Name Total Prescriptions (2017)
Acetaminophen; Hydrocodone Bitartrate 40,123,144
Tramadol Hydrochloride 21,096,313
Oxycodone 15,111,150
Hydrocodone Bitartrate 6,283,981
Morphine 4,090,362
Hydromorphone Hydrochloride 2,530,241
Fentanyl 1,776,409
Loperamide Hydrochloride 731,613
Hydrocodone; Chlorpheniramine 577,813
Codeine Sulfate 430,772

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Tramadol Hydrochloride And Acetaminophen
  • Ultracet
Generic Drug Synonyms and Salts
  • Tramadol Hydrochloride; Acetaminophen
  • Acetaminophen; Tramadol Hydrochloride

FDA Approval Information

Established Pharmacologic Class (EPC): Opioid Agonist
Initial FDA approval date: 8/15/2001
First FDA applicant: Rx
First dosage form: Tablet (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2007-2017. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 20.1. Read more about the ClinCalc DrugStats database.


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Updated Jul 19, 2018
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