Drug Usage Statistics, United States, 2008 - 2018

Acetaminophen Summary for 2018

Estimated number of prescriptions in the United States 27,907,360
Top drug rank #20 ( 5)
Average total drug cost $55.55 (USD)
Average out-of-pocket cost $12.09 (USD)

Number of Prescriptions Over Time (2008 - 2018)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2008 123  34
2009 159  36
2010 203  44
2011 167  36
2012 174  7
2013 19  155
Year Rank Change
2014 17  2
2015 16  1
2016 17  1
2017 25  8
2018 20  5

Drug Cost Over Time (2008 - 2018)

  • Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
  • Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Acephen
  • Infants' Feverall
  • Injectapap
  • Neopap
  • Ofirmev
  • Tylenol
Generic Drug Synonyms and Salts
  • Acetaminophen

FDA Approval Information

Established Pharmacologic Class (EPC): N/A
Initial FDA approval date: Prior to January 1, 1982
First FDA applicant: Otc
First dosage form: Suppository (rectal)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2008-2018. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 21.1. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).


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Updated Jan 18, 2021
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