Drug Usage Statistics, United States, 2004 - 2014

Number of Prescriptions Over Time (2004 - 2014)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2004 279 -
2005 467  188
2006 561  94
2007 432  129
2008 465  33
2009 620  155
Year Rank Change
2010 393  227
2011 295  98
2012 246  49
2013 191  55
2014 258  67

Patient Out-Of-Pocket Cost Over Time (2004 - 2014)

"Out-of-pocket" cost refers to the payment made by the patient (either cash price or the copay amount). This value does not include reimbursement from a third party payer (eg, Medicare or private insurance) and does not represent the total drug cost.

Usage Statistics of Related Drugs

Drug Name Total Prescriptions (2014)
Cyclosporine 2,240,775
Tacrolimus (this drug) 2,026,623

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Astagraf XL
  • Envarsus XR
  • Prograf
  • Protopic
Generic Drug Synonyms and Salts
  • Tacrolimus Anhydrous
  • Tacrolimus

FDA Approval Information

Established Pharmacologic Class (EPC): Calcineurin Inhibitor Immunosuppressant
Initial FDA approval date: 4/8/1994
First FDA applicant: Astellas Pharma Us Inc
First dosage form: Injectable (injection)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2004-2014. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 17.0. Read more about the ClinCalc DrugStats database.


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Updated Mar 4, 2017
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