Drug Usage Statistics, United States, 2004 - 2014

Number of Prescriptions Over Time (2004 - 2014)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2004 5 -
2005 6  1
2006 6 0
2007 7  1
2008 8  1
2009 8 0
Year Rank Change
2010 9  1
2011 9 0
2012 10  1
2013 10 0
2014 10 0

Patient Out-Of-Pocket Cost Over Time (2004 - 2014)

"Out-of-pocket" cost refers to the payment made by the patient (either cash price or the copay amount). This value does not include reimbursement from a third party payer (eg, Medicare or private insurance) and does not represent the total drug cost.

Usage Statistics of Related Drugs

Drug Name Total Prescriptions (2014)
Hydrochlorothiazide (this drug) 50,428,399
Hydrochlorothiazide; Lisinopril 23,095,054
Hydrochlorothiazide; Losartan Potassium 14,028,830
Hydrochlorothiazide; Triamterene 10,970,465
Hydrochlorothiazide; Valsartan 6,148,008
Bisoprolol Fumarate; Hydrochlorothiazide 2,885,296

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Esidrix
  • Hydro-d
  • Hydrochlorothiazide Intensol
  • Hydrodiuril
  • Microzide
  • Oretic
  • Zide
Generic Drug Synonyms and Salts
  • Hydrochlorothiazide

FDA Approval Information

Established Pharmacologic Class (EPC): Thiazide Diuretic
Initial FDA approval date: Prior to January 1, 1982
First FDA applicant: Novartis Pharmaceuticals Corp
First dosage form: Tablet (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2004-2014. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 17.0. Read more about the ClinCalc DrugStats database.


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Which of these drugs causes acute kidney injury? The Top 250 Drugs by ClinCalc Academy
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Updated Mar 4, 2017
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