Glyburide; Metformin Hydrochloride

Drug Usage Statistics, United States, 2004 - 2014

Number of Prescriptions Over Time (2004 - 2014)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2004 107 -
2005 121  14
2006 120  1
2007 121  1
2008 122  1
2009 135  13
Year Rank Change
2010 185  50
2011 215  30
2012 177  38
2013 196  19
2014 232  36

Patient Out-Of-Pocket Cost Over Time (2004 - 2014)

"Out-of-pocket" cost refers to the payment made by the patient (either cash price or the copay amount). This value does not include reimbursement from a third party payer (eg, Medicare or private insurance) and does not represent the total drug cost.

Usage Statistics of Related Drugs

Drug Name Total Prescriptions (2014)
Metformin Hydrochloride 86,125,659
Glipizide 20,700,897
Glimepiride 12,859,037
Glyburide 6,365,008
Metformin Hydrochloride; Sitagliptin Phosphate 3,361,621
Glyburide; Metformin Hydrochloride (this drug) 2,593,237

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Glucovance
  • Glyburide And Metformin Hydrochloride
Generic Drug Synonyms and Salts
  • Glyburide; Metformin Hydrochloride

FDA Approval Information

Established Pharmacologic Class (EPC): Sulfonylurea, Biguanide
Initial FDA approval date: 7/31/2000
First FDA applicant: Bristol Myers Squibb
First dosage form: Tablet (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2004-2014. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 17.0. Read more about the ClinCalc DrugStats database.


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Updated Mar 4, 2017
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