Drug Usage Statistics, United States, 2005 - 2015

Number of Prescriptions Over Time (2005 - 2015)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2004 19 -
2005 22  3
2006 21  1
2007 15  6
2008 18  3
2009 22  4
Year Rank Change
2010 20  2
2011 27  7
2012 44  17
2013 47  3
2014 58  11
2015 66  8

Patient Out-Of-Pocket Cost Over Time (2005 - 2015)

"Out-of-pocket" cost refers to the payment made by the patient (either cash price or the copay amount). This value does not include reimbursement from a third party payer (eg, Medicare or private insurance) and does not represent the total drug cost.

Usage Statistics of Related Drugs

Drug Name Total Prescriptions (2015)
Omeprazole 71,728,531
Pantoprazole Sodium 24,723,892
Esomeprazole (this drug) 13,177,033
Lansoprazole 5,282,850
Dexlansoprazole 2,705,543

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Nexium IV
  • Nexium
  • Nexium 24hr
Generic Drug Synonyms and Salts
  • Esomeprazole Magnesium
  • Esomeprazole Magnesium Dihydrate
  • Esomeprazole Sodium
  • Esomeprazole Strontium
  • Esomeprazole

FDA Approval Information

Established Pharmacologic Class (EPC): Proton Pump Inhibitor
Initial FDA approval date: 2/20/2001
First FDA applicant: Rx
First dosage form: Capsule, Delayed Rel Pellets (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2005-2015. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 18.0. Read more about the ClinCalc DrugStats database.


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Which of these drugs causes acute kidney injury? The Top 250 Drugs by ClinCalc Academy
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Updated Mar 4, 2017
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