Dorzolamide Hydrochloride; Timolol Maleate

Drug Usage Statistics, United States, 2005 - 2015

Number of Prescriptions Over Time (2005 - 2015)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2004 226 -
2005 234  8
2006 185  49
2007 260  75
2008 234  26
2009 203  31
Year Rank Change
2010 246  43
2011 348  102
2012 311  37
2013 262  49
2014 281  19
2015 231  50

Patient Out-Of-Pocket Cost Over Time (2005 - 2015)

"Out-of-pocket" cost refers to the payment made by the patient (either cash price or the copay amount). This value does not include reimbursement from a third party payer (eg, Medicare or private insurance) and does not represent the total drug cost.

Usage Statistics of Related Drugs

Drug Name Total Prescriptions (2015)
Metoprolol 70,473,625
Atenolol 30,034,520
Carvedilol 25,388,562
Propranolol Hydrochloride 13,854,898
Nebivolol Hydrochloride 4,413,473
Dorzolamide Hydrochloride; Timolol Maleate (this drug) 2,359,930
Labetalol 2,263,412
Bisoprolol Fumarate; Hydrochlorothiazide 2,139,244
Dorzolamide Hydrochloride 1,654,881
Atenolol; Chlorthalidone 1,638,392
Nadolol 1,580,003
Bisoprolol Fumarate 1,403,801
Brinzolamide 830,767

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Cosopt
  • Cosopt PF
  • Dorzolamide Hydrochloride And Timolol Maleate
Generic Drug Synonyms and Salts
  • Dorzolamide Hydrochloride; Timolol Maleate

FDA Approval Information

Established Pharmacologic Class (EPC): Carbonic Anhydrase Inhibitor, beta-Adrenergic Blocker
Initial FDA approval date: 4/7/1998
First FDA applicant: Rx
First dosage form: Solution/Drops (ophthalmic)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2005-2015. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 18.0. Read more about the ClinCalc DrugStats database.


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Which of these drugs causes acute kidney injury? The Top 250 Drugs by ClinCalc Academy
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Updated Mar 4, 2017
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