Dorzolamide Hydrochloride; Timolol Maleate

Drug Usage Statistics, United States, 2004 - 2014

Number of Prescriptions Over Time (2004 - 2014)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2004 226 -
2005 234  8
2006 185  49
2007 261  76
2008 235  26
2009 204  31
Year Rank Change
2010 246  42
2011 348  102
2012 311  37
2013 262  49
2014 281  19

Patient Out-Of-Pocket Cost Over Time (2004 - 2014)

"Out-of-pocket" cost refers to the payment made by the patient (either cash price or the copay amount). This value does not include reimbursement from a third party payer (eg, Medicare or private insurance) and does not represent the total drug cost.

Usage Statistics of Related Drugs

Drug Name Total Prescriptions (2014)
Metoprolol 72,320,918
Atenolol 30,837,680
Carvedilol 24,317,623
Propranolol Hydrochloride 9,858,070
Nebivolol Hydrochloride 4,961,231
Atenolol; Chlorthalidone 4,181,880
Bisoprolol Fumarate; Hydrochlorothiazide 2,885,296
Labetalol 2,774,301
Dorzolamide Hydrochloride; Timolol Maleate (this drug) 1,600,800
Nadolol 1,494,872
Brinzolamide 1,271,302
Dorzolamide Hydrochloride 894,891

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Cosopt
  • Cosopt PF
  • Dorzolamide Hydrochloride And Timolol Maleate
Generic Drug Synonyms and Salts
  • Dorzolamide Hydrochloride; Timolol Maleate

FDA Approval Information

Established Pharmacologic Class (EPC): Carbonic Anhydrase Inhibitor, beta-Adrenergic Blocker
Initial FDA approval date: 4/7/1998
First FDA applicant: Oak Pharmaceuticals Inc Subsidiary Of Akorn Inc
First dosage form: Solution/Drops (ophthalmic)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2004-2014. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 17.0. Read more about the ClinCalc DrugStats database.

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Which of these drugs causes acute kidney injury? The Top 250 Drugs by ClinCalc Academy
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Updated Mar 4, 2017
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