Diphenhydramine Hydrochloride

Drug Usage Statistics, United States, 2004 - 2014

Number of Prescriptions Over Time (2004 - 2014)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2004 213 -
2005 186  27
2006 220  34
2007 175  45
2008 239  64
2009 249  10
Year Rank Change
2010 273  24
2011 249  24
2012 259  10
2013 275  16
2014 198  77

Patient Out-Of-Pocket Cost Over Time (2004 - 2014)

"Out-of-pocket" cost refers to the payment made by the patient (either cash price or the copay amount). This value does not include reimbursement from a third party payer (eg, Medicare or private insurance) and does not represent the total drug cost.

Usage Statistics of Related Drugs

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Antitussive
  • Beldin
  • Belix
  • Benadryl
  • Benadryl Preservative Free
  • Benylin
  • Dibenil
  • Diphen
  • Diphenhydramine Hydrochloride Preservative Free
  • Hydramine
  • Silphen
  • Vicks Formula 44
Generic Drug Synonyms and Salts
  • Diphenhydramine Hydrochloride

FDA Approval Information

Established Pharmacologic Class (EPC): N/A
Initial FDA approval date: Prior to January 1, 1982
First FDA applicant: Mcneil Consumer Healthcare
First dosage form: Elixir (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2004-2014. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 17.0. Read more about the ClinCalc DrugStats database.

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Updated Mar 4, 2017
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