Acetaminophen; Tramadol Hydrochloride

Drug Usage Statistics, United States, 2005 - 2015

Number of Prescriptions Over Time (2005 - 2015)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year Rank Change
2004 196 -
2005 286  90
2006 255  31
2007 287  32
2008 300  13
2009 267  33
Year Rank Change
2010 305  38
2011 318  13
2012 338  20
2013 292  46
2014 278  14
2015 274  4

Patient Out-Of-Pocket Cost Over Time (2005 - 2015)

"Out-of-pocket" cost refers to the payment made by the patient (either cash price or the copay amount). This value does not include reimbursement from a third party payer (eg, Medicare or private insurance) and does not represent the total drug cost.

Usage Statistics of Related Drugs

Drug Name Total Prescriptions (2015)
Acetaminophen; Hydrocodone Bitartrate 51,279,738
Tramadol Hydrochloride 24,904,460
Oxycodone 16,887,857
Hydrocodone Bitartrate 9,719,421
Morphine 6,345,800
Fentanyl 2,700,332
Acetaminophen; Tramadol Hydrochloride (this drug) 1,683,637
Hydromorphone Hydrochloride 1,513,925
Loperamide Hydrochloride 1,034,943
Hydrocodone; Chlorpheniramine 319,193

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms
  • Tramadol Hydrochloride And Acetaminophen
  • Ultracet
Generic Drug Synonyms and Salts
  • Tramadol Hydrochloride; Acetaminophen
  • Acetaminophen; Tramadol Hydrochloride

FDA Approval Information

Established Pharmacologic Class (EPC): Opioid Agonist
Initial FDA approval date: 8/15/2001
First FDA applicant: Rx
First dosage form: Tablet (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2005-2015. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 18.0. Read more about the ClinCalc DrugStats database.


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Updated Jul 19, 2018
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